Ovarian Hyperstimuation Syndrome (OHSS) – Dr. Manjushri Kothekar
Every good thing also has some unwanted bad effects. Medicine is not an exception! Here also every treatment, procedure, drug has its own side effects! Ovarian hyper stimulation or OHSS is one among such side effects. Hormonal injections are wont to stimulate the expansion of ovarian follicles within the treatment of IVF. OHSS is one among the side effects of ovarian stimulation.
It is difficult to elucidate the detailed mechanism regarding how it happens. However you’ll read here about what symptoms are expected and the way it are often treated .
Basically in OHSS the blood vessels become leaky. Hence there’s loss of fluid from the blood vessels and therefore the fluid gets accumulated in abdomen . As a result the patient will have symptoms like abdominal fullness, bloating, nausea, vomiting, constipation etc. In severe cases there’ll be dehydration, reduced urine output, accumulation of fluid in cavity , breathlessness , hyper coagubility of the blood etc leading ultimately to multi-organ failure and death.
Thin patients, patients with PCOS(poly cystic ovaries) etc are more susceptible to devlope OHSS. Though it’s impossible to predict it in every case, one can get a thought depending upon the sonographic appearance and hormonal values. Measures are often taken to avoid severe OHSS in such cases.
One important measure is to avoid embryo transfer within the same cycle. All the embryos are often frozen and patient can undergo Frozen Embryo transfer at a later date.
Due to the advances in technology the general incidence of admission for OHSS is sort of low, within the range of two per thousand or so! Still both the patient also because the Doctor need to be vigilant to avoid it!
Dr. Manjushri Kothekar
Consultant – Infertility & IVF Specialist
Currae IVF Centre, Thane, Ghatkopar & Chembur